Tioga Pharmaceuticals, Inc.

About IBS

IBS is a common condition that is found in high prevalence throughout the world. Affected patients experience recurrent episodes of abdominal pain or discomfort associated with a change in bowel pattern, such as loose or more frequent bowel movements, diarrhea, and/or constipation.

In the US, IBS prevalence is estimated to be 15% with a 2:1 ratio of female to male sufferers. Approximately 10% of the general population seeks medical attention for IBS making it the most common diagnosis made by gastroenterologists. While the exact etiology of IBS is unknown, it is believed to be due to a disturbance in the interaction between the intestines, the brain, and the autonomic nervous system that alters regulation of bowel motility or sensory function.

IBS patients fall into different subtypes based on their predominant symptoms. These include IBS with diarrhea (D-IBS), IBS with constipation (C-IBS) and IBS with alternating diarrhea and constipation (A-IBS).