Tioga Novel Therapies
Novel Therapies for the Treatment of Gastrointestinal Diseases
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Tioga Pharmaceuticals Begins Phase 3 Trial of Asimadoline in Irritable Bowel Syndrome

06.03.2010
Tioga Pharmaceuticals, Inc. announced today that the company has dosed its first subject in a Phase 3 clinical trial to evaluate asimadoline for the treatment of patients with diarrhea-predominant irritable bowel syndrome (D-IBS). ...more 
Tioga product asimadoline
Tioga's lead product is asimadoline, a proprietary, peripherally restricted small molecule kappa opioid agonist, originally discovered by Merck KGaA of Darmstadt, Germany.
Asimadoline is currently in Phase 3 clinical development for the treatment of irritable bowel syndrome (IBS) ...more
The Disease
IBS is a common condition that is found in high prevalence throughout the world. Affected patients experience recurrent episodes of abdominal pain or discomfort associated with a change in bowel pattern ...more